Joining me today are Khozema Shipchandler, Chief Executive Officer, Aidan Viggiano, Chief Financial Officer, and Thomas Wyatt, Chief Revenue Officer. Definitions and reconciliations between our GAAP and non-GAAP results can be found in our earnings presentation posted on our IR website at investors.twilio.com. We will also make forward-looking statements on this call, including statements about our future, outlook, and goals. Twilio had a great Q4 as we reached record heights with $1.4 billion in revenue, $256 million of non-GAAP income from operations, and $256 million in free cash flow.
For the full-year, we generated $5.1 billion in revenue, $924 million of non-GAAP income from operations, and $945 million of free cash flow. Reflecting on 2025, Twilio stood out with accelerating revenue growth, expanding operating margins, and by delivering significant growth in free cash flow. In Q4, we saw particular strength in self-serve as revenue grew 28% year-over-year, led by accelerating voice revenue growth. Twilio sent 6.99 billion messages, a 34.5% year-over-year increase, handled 1.07 billion calls, up 58% year-over-year, and processed 75.1 billion emails, a 14.6% increase year-over-year.
Voice year-over-year revenue growth accelerated throughout the year, with customers adopting products like Branded Calling, conversation relay, and conversational intelligence. Additionally, they will use voice software products like conferencing to support additional use cases like multi-party calling or taking payment over the phone. While still early days, during Q4, Twilio's Branded Calling revenue grew roughly 6x year-over-year. We generated record revenue of $1.4 billion, up 14% year-over-year on a reported basis, and 12% year-over-year on an organic basis.