About

Sarah Gheuens, M.D., Ph.D., joined Agios in December 2019, became chief medical officer in September 2021 and took on the additional role of head of R&D in August 2022. She previously served as Agios' head of clinical development for the genetically defined disease programs, as well as interim head of regulatory affairs.

Before joining Agios, Dr. Gheuens worked at Biogen, where she held roles of increasing responsibility in safety, medical affairs and clinical development, and her work was critical for the approval of SPINRAZA.

She holds a Ph.D. in Medical Sciences from the University of Antwerp, Belgium, and a Master's in Medical Sciences from Harvard Medical School.

Roles

Agios Pharmaceuticals, Inc.
Chief Medical Officer, Head of Research & Development · Current role
Sep 2021–present
Agios Pharmaceuticals
Head of clinical development, genetically defined diseases; interim head of regulatory affairs · Joined December 2019 before appointment as chief medical officer.
Biogen
Roles in safety, medical affairs and clinical development
2012 – 2019
Beth Israel Deaconess Medical Center
Physician and researcher · Cared for patients with HIV and neurological complications and researched progressive multifocal leukoencephalopathy.
2008 – 2012
Agios
Head of Clinical Development, Genetically Defined Disease Programs; interim Head of Regulatory Affairs · Earlier roles at Agios before becoming chief medical officer.

External Roles

Viridian Therapeutics
Director; science and technology committee

Fixed Compensation

FY 2025
Base salary
$601,060
Fiscal year2025
All other compensation
$15,694
Fiscal year2025

Performance Compensation

Data from FY 2025

Cash incentive

Non-equity incentive plan compensation
$270,478
FormAnnual cash incentive
Target Opportunity
Evaluation periodFY2025

Stock awards

Stock awards
$397,440
Grant-date fair valueFASB ASC Topic 718
Additional detailsRSUs / PSUs granted in 2025
Option awards
$802,008
Grant-date fair valueFASB ASC Topic 718

Also at Agios Pharmaceuticals, Inc.

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