About

Cynthia Smith has served as a member of the Agios board of directors since August 2022. She is the former chief commercial officer of ZS Pharma.

Earlier, she was vice president of market access and commercial development at Affymax, where she played a key role in launching the company's initial renal medication, and prior to Affymax she held several leadership positions at Merck in market access, corporate and commercial strategy, public policy and external affairs. Before working in the biopharmaceutical industry, she served as a healthcare policy analyst in the White House Office of Management and Budget.

She holds an M.B.A. from the Wharton School of the University of Pennsylvania, an M.S. in public policy from the Eagleton Institute of Politics at Rutgers University, and a B.A. from the University of North Carolina at Chapel Hill.

Roles

Agios Pharmaceuticals, Inc.
Director · Current role
Aug 2022–present
ZS Pharma
Chief Commercial Officer; Executive Committee · Company acquired by AstraZeneca in 2015.
2013 – 2016
Affymax
Vice President, Market Access and Commercial Development
2008 – 2013
Merck & Co.
Senior leadership roles in market access, corporate strategy and government relations
2000 – 2008
White House Office of Management and Budget
Healthcare policy analyst
1995 – 2000
ZS Pharma
Chief Commercial Officer
Merck
Leadership positions in market access, corporate and commercial strategy, public policy and external affairs

External Roles

Akebia Therapeutics
Director
Protara Therapeutics
Director
Spero Therapeutics
Director
Tvardi Therapeutics
Director
French-American Foundation
Director
Protara Therapeutics
Board of Directors
Spero Therapeutics
Board of Directors
Akebia Therapeutics
Board of Directors

Director Compensation

FY 2025
Fees earned or paid in cash
$67,500
Fiscal year2025
Option awards
$299,689
Grant-date fair valueFASB ASC Topic 718
Stock awards
$99,968
Grant-date fair valueFASB ASC Topic 718
Total
$467,157

Also at Agios Pharmaceuticals, Inc.

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