About

Dr. Andrew P. Mazar has served as Actuate Therapeutics' Chief Operating Officer since June 2022, after serving as an independent consultant to the company from January to June 2022. A translational oncology researcher and entrepreneur with over 30 years of experience spanning academia and industry, he was previously Co-Founder, Chief Scientific Officer and a director of Monopar Therapeutics, Inc. from 2016 to 2022, and is a founder and managing member of Tactic Pharma, LLC, where he co-invented WTX-101/ALXN1840 (acquired by Alexion Pharmaceuticals for more than $800 million in 2018). He was previously a Professor of Pharmacology and Director of the Center for Developmental Therapeutics at Northwestern University's Feinberg School of Medicine, and Chief Scientific Officer at Attenuon, LLC. He is a co-author of roughly 150 peer-reviewed publications and a co-inventor on more than 100 patents. Dr. Mazar earned a B.S. in Chemistry from the University of Wisconsin-Parkside and a Ph.D. in Biochemistry from the University of Illinois College of Medicine, Chicago.

Roles

Actuate Therapeutics, Inc.
Chief Operating Officer · Current role
June 2022–present
Actuate Therapeutics, Inc.
Chief Operating Officer
2022 - present
Monopar Therapeutics, Inc.
Co-Founder, Chief Scientific Officer & Director
2016 - 2022
Northwestern University, Feinberg School of Medicine
Professor of Pharmacology; Director, Center for Developmental Therapeutics
2009 - 2016
Attenuon, LLC
Chief Scientific Officer
2000 - 2009

External Roles

Tactic Pharma, LLC
Founder & Managing Member
present

Fixed Compensation

FY 2025
Salary
$450,000
ComponentAnnual base salary earned in 2025
Total compensation
$1,419,569

Performance Compensation

Data from FY 2025

Cash incentive

Bonus
$102,150
Target Opportunity
PlanDiscretionary annual cash bonus

Stock awards

Option awards
$867,419
FormStock options, ASC 718 grant-date fair value

Also at Actuate Therapeutics, Inc.

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