Dr. Mark L. Rubinstein has served as Achieve Life Sciences' Chief Medical Officer since October 2025, having joined as Vice President, Head of Medical Affairs in September 2024 and served as a Medical Affairs consultant from June 2024. Before Achieve he was Head of Medical Affairs at Blip, a smoking-cessation products company, from May 2022 to June 2024, and Vice President, Global Scientific Affairs and Clinical Operations at Juul Labs, Inc. from July 2019 to May 2022. From 2003 to 2019 he was a Professor in the Department of Pediatrics at the University of California, San Francisco, where he is now Professor Emeritus of Pediatrics. Dr. Rubinstein earned his M.D. from Yale School of Medicine, completed his Internal Medicine residency at Yale-New Haven Hospital, and is board certified in Internal Medicine and Adolescent Medicine.