Julian C. Baker has served as an ACADIA director since December 2015. He is a Managing Member of Baker Bros. Advisors LP, a registered investment adviser focused on long-term investments in life-sciences companies, which he co-founded in 2000 with his brother, Felix Baker, Ph.D. He previously was a portfolio manager at Tisch Financial Management and worked in the private-equity arm of Credit Suisse First Boston. He currently serves on the boards of Incyte Corporation, Madrigal Pharmaceuticals and Denali Therapeutics.